As noted by 9to5mac, Apple has enabled an option in the iTunes Store to donate to the American Red Cross for the Japan relief fund. If you want to make your donation to the earthquake and tsunami victims in Japan, you can by visiting this page and choosing to donate $5, $10, $25, $50, $100 or $200. Everything happens through the iTunes account you already have – a clever move to make donations easy and just a click away for iTunes users.
100% of your donation will go to the American Red Cross, which is set to provide food, shelter and assistance to the victims of the earthquake and tsunami.